LEGAL BASIS FOR REGULATION OF THE PRIVATE SECURITY IN THE REPUBLIC OF MACEDONIA



Exploring the crosstalk between endothelial cells, immune cells, and immune checkpoints in the tumor microenvironment: new insights and therapeutic implications

Abstract The tumor microenvironment (TME) is a highly intricate milieu, comprising a multitude of components, including immune cells and stromal cells, that exert a profound influence on tumor initiation and progression.Within the TME, angiogenesis is predominantly orchestrated by endothelial cells (ECs), which foster the proliferation and metastas

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Genetic Analysis and Species Specific Amplification of the Artemisinin Resistance-Associated Kelch Propeller Domain in P. falciparum and P. vivax.

Plasmodium falciparum resistance to artemisinin has emerged in the Greater Mekong Subregion and now poses a threat to malaria control and prevention.Recent work has identified mutations in the kelch propeller domain of the P.falciparum K13 gene to be associated artemisinin resistance as defined by delayed parasite clearance and ex vivo ring stage s

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